I had some serious problems with both the PC Versions of GTAIV and Saints Row 2 and ATI have released a new Graphics card drivers that solve most of the slow downs. Both games run very well now on my PC where as before they would hardly hit 15fps and were unplayable.
GTA IV looks incredable in high-resolutions like 1680*1050 plus of course you need a very good PC but its good to see that it was a Graphics card problem that sorted it all out in the end.
I might add that i run Windows Vista 64 bit as my main O.S and i was getting huge problems with both games until i also ran a Windows Update and installed every single Windows Update that i was missing. It seems the combination of these sorted out the huge slow-down problems i was having.
Saints Row 2 now is playable at last but still makes we wonder if the Xbox 360 version is better.